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KMID : 0616120090400010070
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Korean Journal of Pharmacognosy
2009 Volume.40 No. 1 p.70 ~ p.76
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The Screening of Antibiotics Resistance Inhibition of Herb Drugs entered in Korean Official Formulary (2)-Resistance Inhibition of 36 Essential Oils
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Kim Dong-Myeong
Heo Kyong-Hee
Moon Kyung-Ho
Lee Chung-Kyu
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Abstract
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Thirty six essential oils from herb drugs entered in Korean official formulary, which are frequently used in oriental region, were tested for antibiotic resistance inhibition. When the oils were combined with ampicillin (Am) or amoxicillin (Amx) they showed significant inhibitory effects on the growth of multi-drug resistant Staphylococcus aureus SA2 in considerably low concentration. The most effective combinations were oils from Acanthopanacis Cortex (0.49μg/mL) with Am and Cnidii Rhizoma and Lonicerae Flos (2.77 and 2.79μg/mL, respectively) with Amx as shown in minimum resistance inhibitory concentrations.
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KEYWORD
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essential oil, aromatic herb drug, Acanthopanacis Cortex, Cnidii Rhizoma, Lonicerae Flos, antibiotic-resistance, resistance inhibition, ampicillin, amoxicillin, Staphylococcus aureus SA2
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